| 摘要: |
| [目的]评价脉络通治疗冠心病心绞痛(心血瘀阻证)的有效性和安全性,以复方丹参片为对照药作多中心临床分析。[方法]符合冠心病稳定型劳力性心绞痛西医诊断标准,每周发作心绞痛2次以上的轻度、中度及较重度心绞痛患者,进行分层区组随机、阳性药平行对照、多中心临床研究。试验药脉络通,口服,4片/次,3次/d。疗程4:周;对照药复方丹参片,口服,3片/次3,次/d。疗程:4周。评价治疗冠心病心绞痛(心血瘀阻证)的有效性和安全性。[结果]脉络通组心绞痛疗效、中医证候疗效、心电图疗效及硝酸甘油停减率均与复方丹参片组无统计学差异,疗效较好。且均无不良事件发生。[结论]脉络通治疗冠心病心绞痛心血瘀阻证具有较好疗效,在改善心绞痛方面优于对照药复方丹参片,且临床使用安全。 |
| 关键词: 脉络通 冠心病心绞痛 (心血瘀阻证) 多中心临床研究 |
| DOI：10.11656/j.issn.1673-9043.2010.04.09 |
| 分类号: |
| 基金项目: |
|
| Multi-Center clinical study of Mailuotong treating coronary disease and angina (stagnation of the heard blood) |
|
LI Gui-wei, LIU Xin-qiao, HU Si-yuan
|
|
The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China
|
| Abstract: |
| [Objective] The study is to evaluate the effectiveness and security of mailuotong that treat coronary disease and angina rstagnation of the heard-blood).llle medicine compare with fufangdansen as a control medicine.[Methods] According to west-medicine diagnoses standard of stable and effort angina.Patients who suffering from angina twice a week choosed in this study.The reseach uses lam blocking ran domization.positive parallel controlled design and multi—Center clinical study.Taking Luomaitong is 4pills.three times a day orally for 4 weeks;fufangdansen is 4 pills.three times a day orally for 4 weeks.The study is to evaluat the effectiveness and security of mailuotong that treating coronary disease and angina (stagnation of the heard-blood).[Result] Curative effect of angina.syndrome.EKG and rate of glonoincease of luomaitong group have no statistics difference with fufangdancen group.Either there is noharmful events occured.[Conclusion] To treat coronary disease and angina (stagnation of the heard-blood) ailuotong is better than fufangdansen especially in treating angina also it is more safe. |
| Key words: mailuotong coronary disease and angina (stagnation of the heard blood) multi Center clinical study |
