Home      About this journal      Authors      Referees      Editors      Readers      Archive      Contact us
Systematic review and bayesian network Meta-analysis of traditional Chinese medicine injections for the treatment of non-ST-segment elevation acute coronary syndrome
Hits 197  Download times 187    
View Full Text  View/Add Comment  Download reader
DOI   10.11656/j.issn.1673-9043.2026.07.12
Key Words   non-ST-segment elevation acute coronary syndrome;traditional Chinese medicine injection;network Meta-analysis
Author NameAffiliationE-mail
GUO Junchi Department of Cardiology, Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300250, China
Graduate School, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China 		 
YANG Peili Department of Cardiology, Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300250, China
Graduate School, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China 		 
ZHANG Mingyan School of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China  
ZHAO Yingqiang Department of Cardiology, Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300250, China  
LU Meijuan Department of Cardiology, Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300250, China lmj830127@163.com 
Abstract
    [Objective] To systematically evaluate the efficacy and safety of traditional Chinese medicine（TCM） injections in the treatment of non-ST-segment elevation acute coronary syndrome（NSTE-ACS）and to compare the therapeutic effects of different TCM injections. [Methods] Literature searches were performed in CNKI，Wanfang， VIP，PubMed，Embase，and Web of Science databases from their inception to September 1，2025. Eligible randomized controlled trials（RCTs）were included. Review Manager 5.4 was used for conventional meta-analysis， and R 4.1.2 with RStudio 1.4.1 was employed to conduct Bayesian network meta-analysis using relevant R packages. [Results] A total of 33 RCTs involving 3 181 patients with NSTE-ACS were included. The meta-analysis showed that，compared with conventional Western medical treatment alone，the addition of TCM injections significantly improved overall clinical efficacy and electrocardiogram（ECG）improvement rates，and reduced the incidence of major adverse cardiovascular events（MACE）and C-reactive protein（CRP）levels. The Bayesian network Meta-analysis revealed that：1）for improving total clinical efficacy，Rhodiola Injection > Shuxuetong Injection > Ginkgo-Damole Injection > Shenmai Injection>Danhong Injection. 2）For reducing MACE incidence，Shenmai Injection > Rhodiola Injection > Xuebijing Injection. 3）For lowering CRP levels，Sodium Tanshinone ⅡA Sulfonate Injection > Xuebijing Injection > Danhong Injection. [Conclusion] The combination of TCM injections with conventional Western therapy can improve clinical outcomes in NSTE-ACS patients and demonstrates good efficacy and safety. Although differences exist among various TCM injections，the overall quality of the included studies was low and outcome reporting was incomplete；therefore，further high-quality RCTs are warranted to validate these findings.

You are the 3033579 visitor.

Copyright @ 2007
Address:   Postcode:
Tel:  Fax:  E-mail:
Beijing E-Tiller Co., Ltd.