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Research of major chemical components and pharmacological activities of Epimedium brevicornum Maxim.
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DOI   10.11656/j.issn.1673-9043.2026.08.16
Key Words   Epimedium brevicornum Maxim.;chemical composition;flavanoid;pharmacological activity
Author NameAffiliationE-mail
XU Haoquan Graduate School, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China  
ZHU Feng State Key Laboratory of Generic Manufacture Technology of Chinese Traditional Medicine, Lunan Pharmaceutical Group Co., Ltd., Linyi 276006, China
Shandong New Time Pharmaceutical Co., Ltd., Linyi 276006, China 		 
HUO Zongqing State Key Laboratory of Generic Manufacture Technology of Chinese Traditional Medicine, Lunan Pharmaceutical Group Co., Ltd., Linyi 276006, China
Shandong New Time Pharmaceutical Co., Ltd., Linyi 276006, China 		 
ZHANG Hao State Key Laboratory of Generic Manufacture Technology of Chinese Traditional Medicine, Lunan Pharmaceutical Group Co., Ltd., Linyi 276006, China
Shandong New Time Pharmaceutical Co., Ltd., Linyi 276006, China 		 
YAO Jingchun State Key Laboratory of Generic Manufacture Technology of Chinese Traditional Medicine, Lunan Pharmaceutical Group Co., Ltd., Linyi 276006, China
Shandong New Time Pharmaceutical Co., Ltd., Linyi 276006, China
Lunan Better Pharmaceutical Co., Ltd., Linyi 276006, China 		 
TIAN Xiaoxuan Graduate School, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China  
LIU Zhong Shandong New Time Pharmaceutical Co., Ltd., Linyi 276006, China  
QIN Guofei State Key Laboratory of Generic Manufacture Technology of Chinese Traditional Medicine, Lunan Pharmaceutical Group Co., Ltd., Linyi 276006, China
Shandong New Time Pharmaceutical Co., Ltd., Linyi 276006, China
Lunan Better Pharmaceutical Co., Ltd., Linyi 276006, China 		qinguofei@126.com 
ZHANG Guimin Graduate School, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
State Key Laboratory of Generic Manufacture Technology of Chinese Traditional Medicine, Lunan Pharmaceutical Group Co., Ltd., Linyi 276006, China
Shandong New Time Pharmaceutical Co., Ltd., Linyi 276006, China
Lunan Better Pharmaceutical Co., Ltd., Linyi 276006, China 		lunanzhangguimin@yeah.net 
Abstract
    Epimedium brevicornum Maxim.，a plant of the Berberidaceae family，is a traditional Chinese medicinal （TCM）herb for tonifying deficiency，which is clinically used for the treatment of sexual dysfunction，osteoporosis， and rheumatoid arthritis and other diseases，which has extremely high research value. Studies have shown that there are abundant flavonoids，lignans，terpenes，and polysaccharides in E. brevicornum，with flavonoids being the main components. Most of the compounds have significant pharmacological activities，such as anti-inflammatory，antidepressant，anti-osteoporosisl，anti-aging，antioxidant，and anti-tumor，etc. It has a remarkable therapeutic effect on syndromes such as reproductive system damage，and myocardial infarction. Research progress on 147 chemical components and their multi target pharmacological mechanisms of E. brevicornum were mainly discussed in this paper，in order to fill the deficiency in the existing research regarding componentactivity correlation analysis，to provide a theoretical basis for the in-depth research and development of E. brevicornum.

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