| 摘要: |
| 糖尿病是当前威胁全球人类健康的最重要的非传染性疾病之一，其中20%~40%会发生糖尿病肾病（DN）。DN是糖尿病常见的难治性并发症，早期表现为微量白蛋白尿，继之出现临床蛋白尿，最后进展为慢性肾功能不全，直至终末期肾损害的发生。DN当属中医"消渴"、"水肿"等范畴，病机多为气阴两虚兼瘀滞，治疗上多以补虚、化瘀、去浊为主，在临床上得到显著疗效。 |
| 关键词: 糖尿病肾病 中医药 病机 |
| DOI：10.11656/j.issn.1672-1519.2017.09.20 |
| 分类号:R587.1 |
| 基金项目:国家自然科学基金项目（81373793）。 |
|
| Reserch progress of traditional Chinese medicine therapy for diabetic nephropathy from the pathogenesis prespective |
|
ZHANG Man-ling, ZHANG Ying-wen
|
|
Department of Traditional Chinese Medicine, Zhongnan Hospital of Wuhan University, Wuhan 430071, China
|
| Abstract: |
| Diabetes mellitus(DM) is one of the most important noncommunicable diseases threatening people's health. About 20%~40% people who get DM will have a development of diabetic nephropathy(DN). DN is a common and refractory complication of DN, which has early clinical features as microalbuminuria, then turn to clinical albuminuri a, finally to chronic renal function failure and end stage renal disease. DN should be included in TCM as "Dispersion-thirst disease", "swelling" etc. and its pathogenesis may lie in "deficiency of both qi and yin, accompanied by stasis", so the treatment focus on "tonifying deficiency, stasis-dissolving, turbidity-removal", which has significant curative effect. Based on evidence-based medicine, there have had some researches analyzing the effect of traditional Chinese medicine act on DN from the perspective of pathogenesis, this article will summarize the research progress of it. |
| Key words: diabetic nephropathy traditional Chinese medicine pethogenesis |
