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| Comparative Research on Pharmacodynamics of Different Matching of Danshen and Sanqi-Effect on Myocardial Biochemical Indices of Dog with Experimental Acute Myocardial Ischemia(AMI) |
| Hits 1982 Download times 2265 Received:September 24, 2001 |
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| DOI
10.11656/j.issn.1672-1519.2002.02.24 |
| Key Words
Danshen Root;Sanqi;Pharmacodynamics;cTnI;CK-MB |
| Author Name | Affiliation | | Shang Hongcai | Tianjin University of Traditional Chinese Medicine, Tianjin 300193 | | Zhang Boli | 天津中医学院中医药研究中心, 300193 | | Gao Xiumei | 天津中医学院中医药研究中心, 300193 | | 王怡 | Tianjin University of Traditional Chinese Medicine, Tianjin 300193 | | 康立源 | Tianjin University of Traditional Chinese Medicine, Tianjin 300193 | | 李玉红 | Tianjin University of Traditional Chinese Medicine, Tianjin 300193 | | 杜嵘 | Tianjin University of Traditional Chinese Medicine, Tianjin 300193 | | 江海涛 | Tianjin University of Traditional Chinese Medicine, Tianjin 300193 |
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| Abstract
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| Objective: To observe the effect of 7 different proportions of Danshen Root and Sanqi on myocardial biochemical indiced in dogs with AMI.Methods: AMI model was produced in dog by coronary artery ligation. CTnI and CK-MB concentrations were measured after duodenal administration of drugs. Results: cTnI could be reduced at the proportion of 10/0,10/1,10/3, 10/6,10/10(P<0.05,P<0.01), while CK-MB lowered at the proportion of 10/0,10/1,10/3,10/6.1/10,0/10(P<0.05). Conclusion: The direct effect of Danshen Root on cardiovascular function was better than Sanqi. |
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