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| Effects of Zishen Tiaochong method on ovaries VEGF expression in rats with induced ovulation |
| Hits 1986 Download times 2287 Received:December 30, 2007 |
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| DOI
10.11656/j.issn.1672-1519.2008.02.27 |
| Key Words
Zishen Tiaochong Method;vascular endothelial growth factor;immunohistochemical method;experimental study |
| Author Name | Affiliation | | LI Rui-huan | Tianjin University of TCM, Tianjin 300193, China | | WANG Ling | Tianjin Hospital of Orthopedics, Tianjin 300211, China | | SUN Yan-ming | Tianjin Hospital of Orthopedics, Tianjin 300211, China | | 徐瑾 | 天津中医院 天津 300211 | | 陈静 | Tianjin Hospital of Orthopedics, Tianjin 300211, China | | 张远 | Tianjin Hospital of Orthopedics, Tianjin 300211, China |
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| Abstract
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| [Objective] To observe the effects of Zishen Tiaochong method on ovaries VEGF expression of rats with induced ovulation.[Methods] Eighty rats were randomly divided into four groups: the high-dose and low-dose of GongxueningⅡgroup,positive control group and model group.The VEGF expression at ovary follicular development stage and preovulatory stage of four groups was detected with immunohistochemistry.[Results] During follicular development stage and preovulatory stage,the area,MOD,area%,IOD of GongxueningⅡ group were obviously higher than that of model group.The VEGF expression of preovulatory stage was all higher than that of follicular development stage in four groups.[Conclusions] The molecular mechanism of Zishen Tiaochong Method is possibly concerned with the promotion on ovarial VEGF expression and improvement of follicular blood supply. |
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