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| UPLC-MS fingerprint of Salvia miltiorrhiza Bge. in Bozhou |
| Hits 2156 Download times 1724 Received:February 25, 2015 |
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| DOI
10.11656/j.issn.1672-1519.2015.07.14 |
| Key Words
Salvia miltiorrhiza Bge.;UPLC-MS;fingerprint;quality control |
| Author Name | Affiliation | E-mail | | WANG Yang | The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | | SHI Zhe | The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | | CHEN Tao | The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | | LI Zheng | The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | | CUI Wei-li | The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | | LI Jin | The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | lijin@shitian.com |
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| Abstract
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| [Objective] To study and establish the UPLC-MS fingerprint of Salvia miltiorrhiza Bge. (Danshen), to investigate the stability of different batches of sample for comprehensive evaluation of the quality of Danshen. [Methods] The fingerprint of Danshen (including water-soluble phenolic acids and lipophilic tanshinones) was applied to UPLC-MS, and the similarity of 10 batches of samples was analyzed. The common peak was determined, and identified by the MS data. [Results] The UPLC-MS fingerprint of Danshen was obtained, and 18 common fingerprint peaks were indicated (including 8 water-soluble phenolic acids and 10 lipophilic tanshinones), and 9 of them were identified by comparison with reference standards, and the similarities of the 10 samples were more than 0.90. [Conclusion] The method is reliable and stable, which can be used for the comprehensive evaluation of Danshen. |
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