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| Study on the effect of removing stasis and diffusing yang therapy to LMR and P-selectin of ulcerative colitis rats |
| Hits 2140 Download times 1617 Received:September 13, 2016 |
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| DOI
10.11656/j.issn.1672-1519.2017.05.14 |
| Key Words
resolving stasis and diffusing yang therapy;ulcerative colitis;L/M;P-sel |
| Author Name | Affiliation | | SHI Li-jie | Spleen and Stomach Department, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | BAI Jie-qiong | Affiliated Wuqing Hospital of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301700, China | | LIU Xue | Endoscopy Room, Tianjin People's Hospital, Tianjin 300121, China | | HAO Ran | Spleen and Stomach Department, Qinhuangdao City Hospital of Traditional Chinese Medicine, Qinhuangdao 066000, China |
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| Abstract
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| [Objective] Observed the effect of removing stasis and diffusing yang therapy to LMR and P-selectin of ulcerative colitis rats, while analysis the relationship between the intestinal permeability and P-selectin level.[Methods] Ulcerative colitis model rats were made by DSS, mesalazine enema liquid and removing stasis and diffusing yang (RSDY) herbs in retention edema. The data of L/M and P-sel level were compared aftermolding and before and fater treatment.[Results] It was obviously found that L/M and P-sel level of the model replication group significantly increased comparing with the data of the normal group. The datas of L/M and P-sel level of the group treated by mesalazine and RSDY herbs was obviously less than the data of the model control group, while there was no significant difference between two groups.[Conclusion] Removing stasis and diffusing yang herbs retention enema can reduce L/M and P-sel level of the ulcerative colitis rats, while there was no statistically significant difference comparing with mesalazine group. |
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