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| Exploring the physical function and influencing factors of end-stage renal disease patients from the perspective of integrated traditional Chinese and Western medicine |
| Hits 220 Download times 48 Received:March 01, 2026 |
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| DOI
10.11656/j.issn.1672-1519.2026.06.08 |
| Key Words
end-stage renal disease;physical functionality;traditional Chinese medicine constitutions;integration of traditional Chinese and Western medicine;factors influencing resilience;cross-sectional study |
| Author Name | Affiliation | E-mail | | SONG Xinyuan | Department of Nephrology, Tianjin First Central Hospital, Tianjin 300192, China | | | XU Chuhan | First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China
National Clinical Research Center for Chinese Medicine, Tianjin 300193, China | | | YUAN Tao | Department of Nephrology, Tianjin First Central Hospital, Tianjin 300192, China | | | LI Huanan | First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China
National Clinical Research Center for Chinese Medicine, Tianjin 300193, China
Key Laboratory of Bioeffects of Tuina, National Administration of Traditional Chinese Medicine, Tianjin 300193, China | | | TAN Tao | First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China
National Clinical Research Center for Chinese Medicine, Tianjin 300193, China
Key Laboratory of Bioeffects of Tuina, National Administration of Traditional Chinese Medicine, Tianjin 300193, China | 13072240977@163.com | | CHANG Wenxiu | Department of Nephrology, Tianjin First Central Hospital, Tianjin 300192, China | changwx@sina.com |
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| Abstract
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| [Objective] The study aims to explore the physical function of patients with end-stage renal disease（ESRD）and its influencing factors from the perspective of integrated traditional Chinese and Western medicine，clarify the correlation between traditional Chinese medicine（TCM）constitution and its influencing factors，and provide a basis for optimizing health management pathways. [Methods] A cross-sectional study design was adopted to select 188 maintenance hemodialysis（HD） patients and 242 maintenance peritoneal dialysis（PD）patients from the nephrology outpatient department in 2024. Karnofsky functional status score （KPS）and Pittsburgh sleep quality index（PSQI）were used to evaluate the patients’physical function and sleep quality. International diagnostic criteria for restless leg syndrome（RLS） and the Self Evaluation Scale for Traditional Chinese Medicine Constitution Classification and Determination were used for RLS and constitution determination，and laboratory data were collected. According to the KPS score，patients were divided into Low group（0 to 70 points）and High group（80 to 100 points），and the differences between the groups were compared. Binary logistic regression analysis was applied to explore the influencing factors of physical function in ESRD patients. Spearman analysis was used to investigate the correlation between the influencing factors of KPS and traditional Chinese medicine constitution. [Results] The total incidence of physical dysfunction in ESRD patients in our center is 17.44 %，and the KPS level in HD patients is better than that in PD patients（P<0.05）. Age，serum albumin，and severe RLS are independent influencing factors for low KPS（P<0.05）. Age is positively correlated with yang deficiency，yin deficiency，qi deficiency，and blood stasis（P<0.05），and negatively correlated with damp heat and calmness（P<0.05）. There was no significant correlation between serum albumin and physical constitution（P>0.05）. Severe RLS was positively correlated with yang deficiency，yin deficiency，and blood stasis （P<0.05）. [Conclusion] HD patients have better physical function than PD patients. ESRD patients’physical function is influenced by multiple factors such as age，blood albumin，and severe RLS. TCM constitution is significantly correlated with influencing factors， suggesting that constitution may be involved in regulating physical function. It is recommended to introduce the concept of“tailored to quality”and develop targeted nursing intervention strategies. |
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