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| Study of traditional Chinese medicine syndromes in patients with maintenance hemodialysis combined with sarcopenia and analysis of related influencing factors |
| Hits 2 Download times 0 Received:June 28, 2026 |
| View Full Text View/Add Comment Download reader |
| DOI
10.11656/j.issn.1672-1519.2026.09.04 |
| Key Words
maintenance hemodialysis;sarcopenia;traditional Chinese medicine syndrome;Logistic regression |
| Author Name | Affiliation | E-mail | | LIU Ruxin | Department of Nephrology, Zhongshan Hospital of Traditional Chinese Medicine Affiliated to Guangzhou University of Traditional Chinese Medicine, Zhongshan 528400, China | | | LIN Shuai | Department of Nephrology, Zhongshan Hospital of Traditional Chinese Medicine Affiliated to Guangzhou University of Traditional Chinese Medicine, Zhongshan 528400, China | | | LIU Li | Department of Nephrology, Zhongshan Hospital of Traditional Chinese Medicine Affiliated to Guangzhou University of Traditional Chinese Medicine, Zhongshan 528400, China | | | XU Juan | Department of Nephrology, Zhongshan Hospital of Traditional Chinese Medicine Affiliated to Guangzhou University of Traditional Chinese Medicine, Zhongshan 528400, China | | | LIU Linna | Department of Nephrology, Zhongshan Hospital of Traditional Chinese Medicine Affiliated to Guangzhou University of Traditional Chinese Medicine, Zhongshan 528400, China | | | PANG Jie | Department of Nephrology, Zhongshan Hospital of Traditional Chinese Medicine Affiliated to Guangzhou University of Traditional Chinese Medicine, Zhongshan 528400, China | | | HUANG Lin | Department of Nephrology, Zhongshan Hospital of Traditional Chinese Medicine Affiliated to Guangzhou University of Traditional Chinese Medicine, Zhongshan 528400, China | | | HUANG Qingxiu | Department of Nephrology, Zhongshan Hospital of Traditional Chinese Medicine Affiliated to Guangzhou University of Traditional Chinese Medicine, Zhongshan 528400, China | | | LI Yanlin | Department of Nephrology, Zhongshan Hospital of Traditional Chinese Medicine Affiliated to Guangzhou University of Traditional Chinese Medicine, Zhongshan 528400, China | li.yan.lin@126.com |
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| Abstract
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| [Objective] To investigate the characteristics of traditional Chinese medicine（TCM）syndrome patterns and their associated influencing factors in maintenance hemodialysis（MHD）patients complicated with sarcopenia. [Methods] In this single-center cross- sectional study，199 MHD patients were enrolled. Based on the 2019 Asian Working Group for Sarcopenia（AWGS）diagnostic criteria， patients were divided into a sarcopenia group and a non-sarcopenia group. Clinical data and TCM four diagnostic data were collected， and TCM syndrome patterns and identify associated risk factors were used to be statistical analysis. [Results] The prevalence rate of sarcopenia in this MHD cohort was 30.2%. Compared to the non-sarcopenia group，patients in the sarcopenia group were older，had a higher comorbidity index and prevalence of cerebral infarction，while exhibiting significantly lower body mass index（BMI），a lower proportion engaging in regular exercise，and reduced handgrip strength（P<0.05）. Regarding TCM syndrome patterns，the primary pattern in both groups was spleen-kidney qi deficiency syndrome. The sarcopenia group had a significantly higher proportion of damp- turbidity syndrome（P<0.05），while the non-sarcopenia group had a higher proportion of blood stasis syndrome（P<0.05）. Analysis of syndrome scores revealed that scores for spleen-kidney qi deficiency syndrome，spleen-kidney yang deficiency syndrome，and blood stasis syndrome were all significantly higher in the sarcopenia group compared to the non- sarcopenia group（P<0.05）. Multivariate Logistic regression analysis indicated that advanced age，male gender and lack of exercise were risk factors for sarcopenia，while higher BMI，stronger handgrip strength and blood stasis syndrome were protective factors. [Conclusion] MHD patients with sarcopenia predominantly present with spleen-kidney qi deficiency as the primary pattern and internal obstruction by damp-turbidity as the secondary manifestation. Clinically，factors such as advanced age，male gender，and lack of exercise may increase the risk of sarcopenia in MHD patients. |
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