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Professor ZHANG Boli’experience in treating myasthenia gravis based on the theory of “damp-turbidity and phlegm-rheum”
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DOI   10.11656/j.issn.1672-1519.2026.10.01
Key Words   myasthenia gravis;damp-turbidity;phlegm-rheum;ZHANG Boli;famous doctor experience
Author NameAffiliationE-mail
ZHAO Wen The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, Shenzhen 518000, China  
LIU Xuan The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, Shenzhen 518000, China  
ZHU Jingwen The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, Shenzhen 518000, China  
LI Guangya The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, Shenzhen 518000, China  
LI Peize The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, Shenzhen 518000, China  
HUANG Liuling The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, Shenzhen 518000, China  
LU Yunwei The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, Shenzhen 518000, China
Shenzhen Traditional Chinese Medicine Hospital, Shenzhen 518031, China 
 
JIANG Feng Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China 471770655@qq.com 
QIN Xiude The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, Shenzhen 518000, China
Shenzhen Traditional Chinese Medicine Hospital, Shenzhen 518031, China 
qinxiude@foxmail.com 
Abstract
    Based on Professor ZHANG Boli’s“damp-turbidity and phlegm-rheum”theory,this paper summarizes his clinical experience with myasthenia gravis. He proposes that the core pathogenesis is spleen-kidney deficiency with dampness and blood stasis obstructing the collaterals,rooted in deficiency of the five viscera-mainly the spleen and kidney-often complicated by intermingled dampness and stasis. Staged treatment follows dynamic patterns of the syndrome:the acute phase focuses on eliminating pathogens and unblocking channels;the prolonged phase combines tonification and purgation;the remission phase emphasizes reinforcing qi and strengthening the body’s resistance. Regulating the metabolism of damp-turbidity and phlegm-rheum remains a consistent priority,along with regulating qi flow and nourishing body and spirit,thus providing a systematic framework for long-term myasthenia gravis management.

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