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Chinese medicine master LI Diangui’s experience in treating ulcerative colitis complicated with gangrenous pyoderma based on the theory of“internal turbidity toxin-external ulcer”
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DOI   10.11656/j.issn.1672-1519.2026.10.02
Key Words   ulcerative colitis;pyoderma gangrenosum;turbidity;toxin;ulcer
Author NameAffiliationE-mail
DONG Xiaoyi Hebei Provincial Hospital of Traditional Chinese Medicine, Shijiazhuang 050000, China
Hebei Key Laboratory of Turbidity Toxin Syndrome, Shijiazhuang 050000, China
Hebei Provincial Key Laboratory of Integrated Chinese and Western Medicine for Gastroenterology Research, Shijiazhuang 050000, China
Hebei Technology Innovation Center of Traditional Chinese Medicine Spleen and Kidney Diseases, Shijiazhuang 050000, China 
 
KANG Yong Hebei Provincial Hospital of Traditional Chinese Medicine, Shijiazhuang 050000, China
Hebei Key Laboratory of Turbidity Toxin Syndrome, Shijiazhuang 050000, China 
 
ZHAO Danyang Hebei Provincial Hospital of Traditional Chinese Medicine, Shijiazhuang 050000, China
Hebei Key Laboratory of Turbidity Toxin Syndrome, Shijiazhuang 050000, China
Hebei Provincial Key Laboratory of Integrated Chinese and Western Medicine for Gastroenterology Research, Shijiazhuang 050000, China
Hebei Technology Innovation Center of Traditional Chinese Medicine Spleen and Kidney Diseases, Shijiazhuang 050000, China 
 
HUO Yongli Hebei Provincial Hospital of Traditional Chinese Medicine, Shijiazhuang 050000, China
Hebei Key Laboratory of Turbidity Toxin Syndrome, Shijiazhuang 050000, China
Hebei Provincial Key Laboratory of Integrated Chinese and Western Medicine for Gastroenterology Research, Shijiazhuang 050000, China
Hebei Technology Innovation Center of Traditional Chinese Medicine Spleen and Kidney Diseases, Shijiazhuang 050000, China 
 
XU Weichao Hebei Provincial Hospital of Traditional Chinese Medicine, Shijiazhuang 050000, China
Hebei Key Laboratory of Turbidity Toxin Syndrome, Shijiazhuang 050000, China
Hebei Provincial Key Laboratory of Integrated Chinese and Western Medicine for Gastroenterology Research, Shijiazhuang 050000, China
Hebei Technology Innovation Center of Traditional Chinese Medicine Spleen and Kidney Diseases, Shijiazhuang 050000, China 
 
XU Yapei Hebei Provincial Hospital of Traditional Chinese Medicine, Shijiazhuang 050000, China
Hebei Key Laboratory of Turbidity Toxin Syndrome, Shijiazhuang 050000, China
Hebei Provincial Key Laboratory of Integrated Chinese and Western Medicine for Gastroenterology Research, Shijiazhuang 050000, China
Hebei Technology Innovation Center of Traditional Chinese Medicine Spleen and Kidney Diseases, Shijiazhuang 050000, China 
449428962@qq.com 
Abstract
    Ulcerative colitis(UC),as one of the refractory diseases of the digestive system,not only seriously damages the health and quality of life of patients,but also causes extraintestinal manifestations in patients with long-term disease. Professor LI Diangui,a national medical master,has summarized years of clinical experience and analyzed the same pathogenesis and intrinsic connection between UC and pyoderma gangrenosum(PG)from the perspective of“turbidity toxin”theory. He believes that“internal turbidity toxin”is the basis of the onset of this disease,and the transformation of“internal turbidity toxin external ulce”is its pathological process. By drawing on the method of“eliminating,supporting,and supplementing”in surgical ulcer diseases,he has formulated the treatment principle of“dispelling turbidity toxin,detoxifying,and treating by stages”. The initial attack on evil is to eliminate turbidity toxin,to attack and supplement pus to support turbidity toxin,and to cultivate and supplement positive“qi”in the later stage to clear turbid toxin,in order to provide new ideas for the treatment of UC and its complications.

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