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| Study on the therapeutic effect of modified Banxia Xiexin Decoction combined with aerobic exercise in the treatment of simple obesity in children with spleen deficiency and dampness obstruction syndrome |
| Hits 129 Download times 77 Received:July 14, 2026 |
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| DOI
10.11656/j.issn.1672-1519.2026.10.05 |
| Key Words
modified Banxia Xiexin Decoction;aerobic exercise;simple obesity;clinical therapeutic effect;spleen deficiency and dampness obstruction syndrome |
| Author Name | Affiliation | E-mail | | SHAO Hua | Department of Pediatrics, Changshu Hospital Affiliated to Nanjing University of Chinese Medicine, Changshu 215500, China | | | TAO Limei | Department of Pediatrics, Changshu Hospital Affiliated to Nanjing University of Chinese Medicine, Changshu 215500, China | | | LU Meihua | Department of Pediatrics, Changshu Hospital Affiliated to Nanjing University of Chinese Medicine, Changshu 215500, China | 13962484863@163.com |
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| Abstract
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| [Objective] To investigate the therapeutic effect of modified Banxia Xiexin Decoction combined with aerobic exercise in treating simple obesity in children. [Methods] Totally 96 children with simple obesity were randomly assigned into the control group and the combined group，with 48 cases per group. Then the control group adopted aerobic exercise，and the combined group additionally adopted modified Banxia Xiexin Decoction. The glucose and lipid metabolisms，serum 25-hydroxyvitamin D3 [25-（OH）D3]， body mass index（BMI），Chinese medicine syndrome score，and oxidative stress status were compared between the two groups before and after treatment，and the clinical therapeutic effect and occurrence of adverse reactions of the two groups were also compared. [Results] The combined group had a higher overall effective rate than the control group（P<0.05）. The fasting plasma glucose（FPG）， triglycerides（TG），total cholesterol（TC），body weight，BMI，and Chinese medicine syndrome scores（including physical fatigue， obesity，abdominal distension），and malondialdehyde（MDA）in both groups decreased after treatment，with combined group showing lower results than control group（P<0.05）. The 25-（OH）D3 and superoxide dismutase（SOD）increased in both groups after treatment， and combined group had higher results than control group（P<0.05）. The disappearance rate of fatigue，obesity and abdominal distension in the traditional Chinese medicine syndrome score of the combined group was better than that of the control group（P< 0.05）. There was no significant difference in the total adverse reactions between the two groups（P>0.05）. [Conclusion] The modified Banxia Xiexin Decoction combined with aerobic exercise can effectively improve glucose and lipid metabolisms，reduce insulin resistance，and decrease lipid accumulation in children with simple obesity，which helps to reduce the risk of cardiovascular disease and has remarkable therapeutic effects. |
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