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Study strategy on color consistency of traditional Chinese medicine placebo based on intelligent color fitting and evaluation technology
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DOI   10.11656/j.issn.1672-1519.2026.10.08
Key Words   traditional Chinese medicine preparation;traditional Chinese medicine placebo;color simulation;color evaluation;similarity
Author NameAffiliationE-mail
TENG Tingting National Key Laboratory of Modern Chinese Medicine Innovation and Manufacturing, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
Tianjin Modern Innovation Chinese Medicine Technology Co., Ltd., Tianjin 300380, China 
 
CHEN Jingmei National Key Laboratory of Modern Chinese Medicine Innovation and Manufacturing, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
Tianjin Modern Innovation Chinese Medicine Technology Co., Ltd., Tianjin 300380, China 
 
LIU Dailin Tianjin Modern Innovation Chinese Medicine Technology Co., Ltd., Tianjin 300380, China
Haihe Laboratory of Modern Chinese Medicine, Tianjin 301617, China 
 
SONG Xinbo National Key Laboratory of Modern Chinese Medicine Innovation and Manufacturing, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
Tianjin Modern Innovation Chinese Medicine Technology Co., Ltd., Tianjin 300380, China 
 
ZHANG Jingze National Key Laboratory of Modern Chinese Medicine Innovation and Manufacturing, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
Tianjin Modern Innovation Chinese Medicine Technology Co., Ltd., Tianjin 300380, China 
zhangjingze1977@163.com 
ZHANG Junhua National Key Laboratory of Modern Chinese Medicine Innovation and Manufacturing, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
Haihe Laboratory of Modern Chinese Medicine, Tianjin 301617, China 
zjhtcm@foxmail.com 
Abstract
    As a key control tool for evaluating the true efficacy of drugs in clinical trials,the simulation accuracy of sensory characteristics of traditional Chinese medicine placebos directly affects the scientificity of double-blind design and subject compliance. Color is the most intuitive first impression,and the color similarity of placebos directly affects patients’trust in treatment. At present, the color fitting of traditional Chinese medicine placebos is undergoing technological innovation from empirical trial and error to intelligent prediction. This article systematically elaborates on the progress in color simulation and evaluation of traditional Chinese medicine placebos,summarizes current technological means,and proposes useful solutions to existing problems and challenges,in order to provide theoretical support for the modernization of traditional Chinese medicine placebos.

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