| 摘要: |
| [目的] 观察跷维阳刺法联合贴扎治疗风寒型特发性周围性面瘫的临床疗效及对血清白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)水平的影响。[方法] 将 120 例风寒型特发性周围性面瘫患者随机分为对照组与针贴组。两组均予基础治疗(激素、营养神经、抗病毒药物及康复训练)及跷维阳刺法治疗,针贴组加用贴扎治疗,疗程3 周。比较两组治疗前后 House-Brackmann(H-B)分级、面部残疾指数(FDI)评分、中医症状积分及血清 IL-6、TNF-α水平,评价疗效并记录不良反应。[结果] 两组临床疗效比较,针贴组有效率达 89.83%,对照组有效率为 74.14%,针贴组疗效明显优于对照组(P<0.05)。两组量表评分变化,两组治疗后 H-B 分级均降低,FDI 评分(功能和社会心理)均升高,组内治疗前后比较差异有统计学意义(P<0.05)。针贴组治疗后 H-B 分级更低,FDI 评分提升幅度更大,组间比较差异有统计学意义(P<0.05),表明针贴组在改善面神经功能和面部残疾程度方面更具优势。两组治疗后血清 IL-6、TNF-α 水平均下降,组内比较差异有统计学意义(P<0.05)。针贴组下降更显著,组间比较差异有统计学意义(P<0.05)。炎症因子水平下降越明显,疗效越好,提示其与疗效呈负相关。安全性评价,两组不良反应均较轻微,经处理后未影响后续治疗。[结论] 跷维阳刺法联合贴扎治疗风寒型特发性周围性面瘫可显著提升临床疗效,能更有效降低 H-B 分级、提高面部 FDI 评分,并显著降低血清 IL-6、TNF-α 等炎症因子水平。该联合方案可有效改善患者面神经功能及临床症状,缩短治愈疗程,且不良反应轻微、安全性良好。 |
| 关键词: 跷维阳刺法 贴扎治疗 周围性面瘫 血清因子 临床疗效 |
| DOI:10.11656/j.issn.1672-1519.2026.10.04 |
| 分类号:R246 |
| 基金项目:山东省自然科学基金项目(ZR2023LZY026);山东省中医药科技项目(M20251505)。 |
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| Clinical study on the Qiaoweiyang acupuncture method combined with taping therapy in the treatment of wind-cold type idiopathic peripheral facial paralysis |
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WANG Huikai, ZHUANG Hua, WANG Fei, YANG Yanhong, WANG Xiaoying, ZHANG Xuanjing
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Department of General Practice, Binzhou Hospital of Traditional Chinese Medicine(Affiliated Hospital of Traditional Chinese Medicine, Binzhou Medical University), Binzhou 256600, China
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| Abstract: |
| [Objective] To observe the clinical efficacy of Qiaoweiyang acupuncture combined with taping therapy in the treatment of wind-cold type idiopathic peripheral facial paralysis and its influence on the levels of serum IL-6 and TNF-α. [Methods] A total of 120 patients with wind-cold type idiopathic peripheral facial paralysis were randomly divided into a control group and an acupuncture-taping group. Both groups received basic treatment(hormones,neurotrophic agents,antiviral drugs and rehabilitation training)and Qiaoweiyang acupuncture,while the acupuncture-taping group was additionally given taping therapy,with a course of 3 weeks. The h-b grading,facial disability index(FDI)scores,traditional chinese medicine(TCM)symptom scores and serum IL-6,TNF-α levels of the two groups before and after treatment were compared to evaluate the curative effect and record adverse reactions. [Results] Comparison of clinical efficacy between the two groups:the effective rate of the acupuncture-taping group reached 89.83%,and that of the control group was 74.14%,indicating that the curative effect of the acupuncture-taping group was significantly better than that of the control group(P<0.05). Changes of scale scores in the two groups:after treatment,the H-B grading of both groups decreased,and the FDI scores(functional and psychosocial)increased;there were statistically significant differences in the intra-group comparisons before and after treatment(P<0.05). After treatment,the H-B grading of the acupuncture-taping group was lower,and the improvement of FDI scores was greater,with statistically significant differences between the two groups(P<0.05),suggesting that the acupuncture-taping group had more advantages in improving facial nerve function and the degree of facial disability. After treatment,the serum IL-6 and TNF-α levels of both groups decreased,with statistically significant differences in intra-group comparisons(P<0.05). The decrease in the acupuncture-taping group was more significant,and there was a statistically significant difference between the two groups(P<0.05). The more obvious the decrease of inflammatory factor levels,the better the curative effect,suggesting a negative correlation between inflammatory factors and curative effect. Safety evaluation:the adverse reactions of both groups were mild,and did not affect subsequent treatment after treatment. [Conclusion] Qiaoweiyang acupuncture combined with taping therapy can significantly improve the clinical efficacy in the treatment of wind-cold type idiopathic peripheral facial paralysis,which can more effectively reduce H-B grading,increase facial FDI scores,and significantly decrease the levels of serum IL-6,TNF-α and other inflammatory factors. This combined scheme can effectively improve the facial nerve function and clinical symptoms of patients,shorten the treatment course,with mild adverse reactions and good safety. |
| Key words: Qiaoweiyang acupuncture method kinesiology taping therapy peripheral facial paralysis serum factor clinical efficacy |