| 摘要: |
| 目的: 复制大鼠湿热证模型。方法: 采用多因素复合造模法。以饮食失调造成内湿环境,以提高空气温度与湿度,外加感染鼠伤寒杆菌模拟外感湿热病邪,内外合邪造模。结果: 造模大鼠体温、饮食量、饮水量、尿量、体重、二便、舌象、精神状态出现变化,符合湿热证的特点,舌、肠、肝、脾也出现病理变化,运用三仁汤治疗有效。结论: 用以上方法可成功地复制湿热证模型。 |
| 关键词: 湿热证模型 大鼠 三仁汤 |
| DOI：10.11656/j.issn.1672-1519.2002.02.22 |
| 分类号: |
| 基金项目:天津市卫生局科研基金资助项目(993606411) |
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| Reproduce Rat Model of Dampness-heat Syndrome and Experimental Observation on the Effect of San Ren Tang(Decoction of Three Kinds of Kernels) |
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Chen Shuangbai, Chang Shufeng, Xiao Zhaocen
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Tianjin University of Traditional Chinese Medicine, Tianjin 300193
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| Abstract: |
| Objective: To reproduce the rat model of Dampness-heat syndrome. Methods: It was made by compound methods with several factors, including endogenous dampness produced by diet disorder and exopathogenic dampness-heat by high air temperature and humidity.Thus, the model was made by using both exopathic and endopathic evil factoros. Results: There were some changes coincided with the characteristics of dampness-heat syndrome in the model rat, such as body temperature, diet and water intake, urine output, body weight,urination and defecation, tongue picture, mental state etc.Pathological changes also occurred in tongue, intestine, liver and spleen. San Ren Tang was effective for treating this disease. Conclusion: The model of dampness-heat syndrome in rat could be reproduced successfully by the method mentioned above. |
| Key words: Model of dampness-heat syndrome Rat San Ren Tang |
