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张伯礼教授基于“湿浊痰饮”辨治重症肌无力经验
赵稳1, 刘璇1, 朱静文1, 李光亚1, 李沛泽1, 黄柳玲1, 陆韵薇1,2, 江丰3, 秦秀德1,2
1.广州中医药大学第四临床医学院, 深圳 518000;2.深圳市中医院, 深圳 518031;3.天津中医药大学, 天津 301617
摘要:
基于国医大师张伯礼教授湿浊痰饮类病学说,阐述治疗重症肌无力的临证经验。张教授认为重症肌无力的核心病机是脾肾虚损、湿瘀阻络,其本在五脏虚损,尤以脾肾为要,兼见湿瘀胶结为患。根据重症肌无力不同阶段的动态证候,治疗上主张分期论治,急性期祛邪开壅,迁延期攻补兼施,缓解期扶正固本。其治法将痰浊水饮的代谢调节贯穿于诊治,兼顾调畅气机、形神共养,为重症肌无力的长期管理提供了系统思路。
关键词:  重症肌无力  湿浊  痰饮  张伯礼  名医经验
DOI:10.11656/j.issn.1672-1519.2026.10.01
分类号:R746.1
基金项目:国家自然科学基金项目(82405265);广东省中医药局科研项目(20242075);深圳市科技计划项目(JCYJ20230807094817035、JCYJ20250604145804006);深圳市医学研究专项基金(C2501006)。
Professor ZHANG Boli’experience in treating myasthenia gravis based on the theory of “damp-turbidity and phlegm-rheum”
ZHAO Wen1, LIU Xuan1, ZHU Jingwen1, LI Guangya1, LI Peize1, HUANG Liuling1, LU Yunwei1,2, JIANG Feng3, QIN Xiude1,2
1.The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, Shenzhen 518000, China;2.Shenzhen Traditional Chinese Medicine Hospital, Shenzhen 518031, China;3.Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
Abstract:
Based on Professor ZHANG Boli’s“damp-turbidity and phlegm-rheum”theory,this paper summarizes his clinical experience with myasthenia gravis. He proposes that the core pathogenesis is spleen-kidney deficiency with dampness and blood stasis obstructing the collaterals,rooted in deficiency of the five viscera-mainly the spleen and kidney-often complicated by intermingled dampness and stasis. Staged treatment follows dynamic patterns of the syndrome:the acute phase focuses on eliminating pathogens and unblocking channels;the prolonged phase combines tonification and purgation;the remission phase emphasizes reinforcing qi and strengthening the body’s resistance. Regulating the metabolism of damp-turbidity and phlegm-rheum remains a consistent priority,along with regulating qi flow and nourishing body and spirit,thus providing a systematic framework for long-term myasthenia gravis management.
Key words:  myasthenia gravis  damp-turbidity  phlegm-rheum  ZHANG Boli  famous doctor experience
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